Massachusetts State Board Esthetics Practice Exam

Desmosomes are crucial for what function in the skin?

1. Producing melanin

2. Holding cells together

3. Forming the barrier layer

4. Creating keratin granules

The correct answer is: Holding cells together

Desmosomes are specialized structures that play a critical role in maintaining the integrity of the skin by holding cells together. They are intercellular junctions that link the cytoskeletons of adjacent cells, allowing for strong adherence and creating a cohesive cellular structure. This is particularly important in the skin, where cells must withstand mechanical stress and prevent separation, especially in areas subject to friction and movement. The other functions listed, such as producing melanin, forming the barrier layer, and creating keratin granules, are carried out by different types of cells and systems within the skin. For instance, melanocytes are responsible for melanin production, while the stratum corneum contributes to the barrier layer of the skin. Keratinocytes produce keratin, and while they may have keratin granules, this is not the role of desmosomes. Thus, the primary importance of desmosomes lies in their function of integrity and cohesion among skin cells.